Oxford Street’s car-free shift is offering a £2.8bn boost, but tight delivery windows could create a puzzle for retail and supply chain leaders. London’s Oxford Street is undergoing a major transformation aimed at revitalizing the area in response to the pandemic and the rise of online shopping. The pedestrianization plan, approved by Mayor Sadiq Khan, seeks to make Oxford Street competitive with New York's Fifth Avenue and Paris's Champs-Élysées. This shift from transactional to experiential retail is expected to attract more visitors and boost sales, despite a 36% drop in prime rental values since the pandemic. However, the transformation introduces operational complexities for supply chain professionals, as service and delivery vehicles are restricted to midnight to 7 a.m. access, necessitating operational reconfiguration, including night-time inventory management and noise control protocols. Major retailers are piloting integrated delivery models to reduce vehicle movements. The transformation is anticipated to attract new investment, create jobs, and contribute significantly to London's economy, with Oxford Street accounting for approximately £25 billion of the UK's total economic output.